The most desired formula among specialists

TrioGLA+ is the first composition of plant oils in Poland based solely on the richest known sources of gamma-linolenic acid (GLA):

  • evening primrose oil
  • borage oil
  • blackcurrant seed oil
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Shipping time: up to 3 working days. Shipping time may be extended in case of increased order quantities.

A combination of oils with the highest GLA content

1

Support yourself with PMS, PCOS and peri- and postmenopausal symptoms

2

Support the regulation of lipid metabolism in weight disorders and metabolic diseases

3

Strengthen the anti-inflammatory potential of dietary interventions

4

Support the skin's protective function in conditions following dermatological and cosmetological treatments

Author of the TrioGLA+ formula

“GLA stands out for its remarkable spectrum of health properties, which is confirmed by numerous clinical studies conducted worldwide. Due to its strong anti-inflammatory effects, particularly when combined with EPA and DHA, it can provide valuable support for chronic inflammatory conditions. In the era of modern lifestyle, where we inevitably lose crucial gut microbiome functions related to immune regulation, strengthening the anti-inflammatory potential of our diet should be a key intervention. Therefore, when developing the oil recipe, our goal was also to maximise the use of the richest known sources of GLA”

doktor mikrobiom

Anti-Inflammatory Formula

TrioGLA+ is a unique combination of cold-pressed oils that is distinguished by its high content of gamma-linolenic acid (GLA) and oleic acid.

Gamma-linolenic acid is an essential element for the production of prostaglandin E1, which is a key compound in the regulation of inflammatory processes. Thanks in part to these transformations, as well as the reduction of pro-inflammatory mediators and reactive oxygen species during inflammation, GLA is considered to be a compound with anti-inflammatory, antioxidant, antithrombotic, lipid-lowering, and tissue-regenerating properties.

In light of current knowledge, GLA may play a crucial role, especially in the nutrition of patients with non-alcoholic fatty liver disease and atherosclerosis, as it has a regulating effect on lipid metabolism and reduces their accumulation in the body. Additionally, it may provide helpful support in the course of autoimmune diseases, skin inflammation, and painful menstruation.

On the other hand, oleic acid has a beneficial effect on the functioning of the heart and circulatory system, as it reduces the concentration of total cholesterol and LDL cholesterol in the blood serum, increases the concentration of HDL cholesterol, and prevents the formation of atherosclerotic plaque. Research results also suggest that consuming oleic acid can help regulate blood glucose levels and improve cell insulin sensitivity. Additionally, like GLA, it has clinically documented anti-inflammatory properties and acts as a potent antioxidant, which translates into its high potential in alleviating symptoms associated with prolonged inflammatory states.

Support for Women's Health Issues

The combination of evening primrose oil, borage oil, and blackcurrant seed oil may be particularly useful for women with hormonal imbalances, such as polycystic ovary syndrome or during the peri- and postmenopausal period.

These oils contain many biologically active compounds, including gamma-linolenic acid, which can help alleviate symptoms associated with hormonal imbalance, such as menstrual pain, vaginal and skin dryness, emotional instability, and hot flashes. All of these psychophysical symptoms can occur in women during the perimenopausal and menopausal periods.

The effectiveness of the dominant ingredient in our blend, evening primrose oil, is explained by its high content of phytoestrogens, which partially compensate for the natural decline in oestrogen during menopause. Studies suggest that evening primrose oil in the right dose reduces the severity of night sweats, hot flashes and mood changes. For similar reasons, its use is also suggested for severe premenstrual syndrome. With systematic and prolonged supply, it succeeds in significantly easing PMS symptoms.

With its anti-inflammatory, antioxidant and cardioprotective properties, the TrioGLA+ oil blend can be a valuable addition to any woman’s nutrition.

Supporting the treatment of dermatoses and rebuilding the natural immunity of the skin.

The mixture of oils from evening primrose, borage and blackcurrant seeds can be an effective support for people with skin problems, hair loss and support regeneration of the epidermal barrier after cosmetic and dermatological procedures.

Supplementation of GLA in the appropriate dose can improve the quality and appearance of acne-prone skin, as well as increase the effectiveness of standard treatment. Due to its immune system-modulating effects, restoring the stratum corneum lipid barrier, reducing transepidermal water loss and improving conditions for recolonisation by the physiological microbiota, gamma-linolenic acid (GLA) can support the treatment of any type of acne, help reduce the severity of psoriasis, eczema and successively improve skin tolerance to irritants, including active substances contained in cosmetics.

The blackcurrant seed oil, which constitutes as much as 20% of the mixture, should be treated in a special way in terms of cosmetic action. Not only because of the abundance of GLA and an extremely favourable ratio of omega-3 and omega-6 fatty acids, similar to fish oils, but also due to the presence of a number of other biologically active compounds such as stearidonic acid, vitamin E, carotenoids, flavonoids, and phenolic acids. Because of these factors, blackcurrant seed oil is characterised by exceptionally strong anti-inflammatory and antioxidant properties used to improve the condition of problematic skin. Additionally, research suggests its beneficial effect in slowing down hair loss and nourishing hair.

According to current knowledge, the use of evening primrose oil, borage oil, and blackcurrant seed oil can help reduce inflammation, soothe irritations and dryness of the skin, as well as support the natural immunity of already stabilised skin.

Counteracting the loss of gut microbiome diversity

The diversity and species richness of the microbiome is a critical parameter of the functioning of the entire ecosystem…

… and its implementation of the protective functions required by the human body. Moreover, leading researchers on the gut microbiome of industrialized populations see the loss of gut microbiome diversity as a health threat on par with climate change.

In the light of current data, the strongest factor impoverishing the intestinal microbiome are metabolic disorders. Patients with worsening abnormalities in blood lipids and glucose levels show the greatest long-term damage to the microbiome, which consistently follows changes in host physiology during the transition to a disease state.

In Poland, metabolic disorders constitute a huge clinical problem. Polish children are gaining weight the fastest in Europe, abnormal lipid profiles affect over 70% of adults, 25% have non-alcoholic fatty liver disease, and nearly 5 million Poles have prediabetes.

Therefore, supplementing nutrition with evening primrose, borage and blackcurrant seed oil, which have clinically documented beneficial effects on metabolic parameters crucial for maintaining the diverse intestinal ecosystem that controls all mucosal immunity, can be an extremely helpful intervention.

Highest concentration of functional oils in one bottle

0 g/100g
GLA Acid

Borage seed oil

Borage seed oil consists mainly of essential unsaturated fatty acids, including gamma-linolenic acid (GLA) constituting over 20% of the total volume, as well as the extremely valuable oleic acid. It is worth mentioning that it is the richest source of GLA among vegetable oils. Other valuable ingredients of borage seed oil are: flavonoids, tannins, iron, zinc, magnesium, calcium, copper, manganese and potassium. Interestingly, borage seed oil has a clinically proven effect on the recovery of people after respiratory infections. Researchers say it helps improve lung function in people with respiratory infections and disorders such as acute respiratory distress syndrome and COVID-19. In TrioGLA+, borage seed oil constitutes 40% of the mixture.

Evening primrose seed oil

Evening primrose oil is characterized by a high content of gamma-linolenic acid (GLA), which is around 9-10%. Additionally, it contains zinc, selenium, magnesium, calcium, phytosterols, vitamin E and numerous anti-inflammatory polyphenol compounds. It is not without reason that it is called the best friend of healthy skin for a reason. It makes up 35% of the TrioGLA+ composition.

Blackcurrant seed oil

Blackcurrant seed oil is the second, after borage, richest source of gamma-linolenic acid (up to 17% of the total volume), however, unlike them, it is also rich in n-3 PUFA: alpha-linolenic acid and stearidic acid (as one of few vegetable oils!), Comparable to fish oils in this aspect. Moreover, blackcurrant seed oil is one of the richest in vitamin E among vegetable oils. It also contains phytosterols, carotenoids, flavonoids and phenolic acids. Due to the abundance of so many biologically active compounds, this oil has strong immunomodulatory and antioxidant properties, successfully used to improve the condition of people suffering from cardiovascular or rheumatic diseases. Its cosmetic effect seems to be particularly promising in dermatoses and the problem of thin and sparse hair. Blackcurrant seed oil constitutes 25% of the TrioGLA+ composition.

  • Uncompromising selection of ingredients
  • A combination of oils with the highest GLA content
  • The percentage of each ingredient given on the label

 179,00 zł

PojemnośćCapacity: 250 ml 

order now

Shipping time: up to 3 working days. Shipping time may be extended in case of increased order quantities.

Frequently Asked Questions

If you haven’t found the answer to your question, please contact us by e-mail or telephone.

To maintain the full nutritional properties and freshness of the product, it is recommended to store TrioGLA+ in a dry and cool place, out of reach of children, away from sunlight and heat sources.

After opening, the product should be kept in the fridge and consumed within 2 months.

The recommended daily intake of TrioGLA+ is 5-10 ml per day, preferably taken during meals. It can be consumed on its own or added to salads, coleslaw, dressings, smoothies, and other cold dishes.

We recommend taking TrioGLA+ only after a meal.

TrioGLA+ can be consumed alone or added to salads, coleslaw, dressings, smoothies and other cold dishes.

THE OIL SHOULD ONLY BE CONSUMED COLD.

11. TrioGLA+ in an individually adjusted dose (2.5-5ml) is suitable for children over 3 years old.

Pregnant and breastfeeding women should consult a doctor before using the product.

TrioGLA+ as a food product does not have strict recommendations regarding its use and does not pose a risk of overdose.

It is worth introducing TrioGLA+ as a permanent element of the diet without having to interrupt its use.

If in doubt, we always recommend consulting a specialist who will be able to assess whether continuing to use the product at the current dose is appropriate for your case.

Science publications

The composition of TrioGLA+ and all substantive content were prepared based on the latest scientific reports.

  1. Mrozińska M. Rola kwasu gamma-linolenowego w utrzymaniu prawidłowej struktury i funkcji skóry. Czasopismo Aptekarskie. 2018; Nr 1 (169). Str. 50-52
  2. Cheng- Yu Lin , Ching-Yun Hsu, Ahmed O Elzoghby et al. Oleic acid as the active agent and lipid matrix in cilomilast-loaded nanocarriers to assist PDE4 inhibition of activated neutrophils for mitigating psoriasis-like lesions. Acta Biomaterialia. 2019;90:350-361.
  3. Liang Y., Zhang Z., Tu J. et al: γ-linolenic acid prevents lipid metabolism disorder in palmitic acid-treated alpha mouse liver-12 cells by balancing autophagy and apoptosis via the LKB1-AMPK-mTOR pathway. J Agric Food Chem. 2021, 28;69(29): 8257-8267
  4. Johnson MM, Swan DD, Surette ME et al. Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans. J Nutr. 1997 Aug;127(8):1435-44. 
  5. Hooper L, Al-Khudairy L, Abdelhamid AS et al. Omega-6 fats for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2018 Nov 29;11(11):CD011094.
  6. DiSilvestro RA, Olivo Marston S, Zimmerman A et al. Borage oil intake by overweight young adults: no effect on metabolic rate; beneficial effects on plasma triglyceride and HDL cholesterol readings. Food Funct. 2021 Oct 4;12(19):8882-8886.
  7. D Prabhu Y, Valsala Gopalakrishnan A. γ-Linolenic acid ameliorates DHEA induced pro-inflammatory response in polycystic ovary syndrome via PPAR-γ signaling in rats. Reprod Biol. 2020 Sep;20(3):348-356.
  8. D Prabhu Y, Bhati M, Vellingiri B, Valsala Gopalakrishnan A. The effect of γ-linolenic acid on Polycystic Ovary Syndrome associated Focal Segmental Glomerulosclerosis via TGF-β pathway. Life Sci. 2021 Jul 1;276:119456.
  9. Niamh Phelan, Annalouise O’Connor, Tommy Kyaw T. et al. Hormonal and metabolic effects of polyunsaturated fatty acids in young women with polycystic ovary syndrome: results from a cross-sectional analysis and a randomized, placebo-controlled, crossover trial–, The American Journal of Clinical Nutrition, Volume 93, Issue 3, March 2011, Pages 652–662.
  10. Yahay, M., Heidari, Z., Allameh, Z. et al. The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a randomized controlled trial. Lipids Health Dis 20, 7 (2021).
  11. Rachtan-Janicka J., Ponder A., Hallmann E. The Effect of Organic and Conventional Cultivations on Antioxidants Content in Blackcurrant (Ribes nigrum L.) Species. Appl. Sci. 2021;11:5113.
  12. Pieszka M., Migdał W., Gąsior R. et al. Native oils from apple, blackcurrant, raspberry, and strawberry seeds as a source of polyenoic fatty acids, tocochromanols, and phytosterols: A health implication. J. Chem. 2015;2015:659541.
  13. Trela A., Szymańska R. Less widespread plant oils as a good source of vitamin E. Food Chem. 2019;296:160–166.
  14. Jurgoński A., Fotschki B., Juśkiewicz J. Disparate metabolic effects of blackcurrant seed oil in rats fed a basal and obesogenic diet. Eur. J. Nutr. 2015;54:991–999.
  15. Linnama P., Nieminen K., Koulu L. et al. Black currant seed oil supplementation of mothers enhances IFN-c and suppresses IL-4 production in breast milk. Pediatr. Allergy Immunol. 2013;24:562–566.
  16. Linnamaa P., Savolainen J., Koulu L. et al. Blackcurrant seed oil for prevention of atopic dermatitis in newborns: A randomized, double-blind, placebo-controlled trial. Clin. Exp. Allergy. 2010;40:1247–1255.
  17. Zhao F., Wu Z., Hou Y. et al. Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytother. Res. 2010;24:S209–S213.
  18. Deferne J.L., Leeds A.R. Resting blood pressure and cardiovascular reactivity to mental arithmetic in mild hypertensive males supplemented with blackcurrant seed oil. J. Hum. Hypertens. 1996;10:531–537.
  19. Laitinen K, Sallinen J, Linderborg K, Isolauri E. Serum, cheek cell and breast milk fatty acid compositions in infants with atopic and non-atopic eczema. Clin Exp Allergy 2006, 36: 166-173.
  20. Le Floc’h C, Cheniti A, Connétable S, et al. Effect of a nutritional supplement on hair loss in women. J Cosmet Dermatol 2014, 14: 76-82
  21. Jung JY, Kwon HH, Hong JS et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. Acta Derm Venereol. 2014 Sep;94(5):521-5. 
  22. Veselinovic M, Vasiljevic D, Vucic V et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017 Mar 25;9(4):325.
  23. Kaźmierska A, Bolesławska I, Jagielski P et al. Effect of Evening Primrose Oil Supplementation on Biochemical Parameters and Nutrition of Patients Treated with Isotretinoin for Acne Vulgaris: A Randomized Double-Blind Trial. Nutrients. 2022 Mar 23;14(7):1342.
  24. Khorshidi M, Zarezadeh M, Moradi Moghaddam O et al. Effect of evening primrose oil supplementation on lipid profile: A systematic review and meta-analysis of randomized clinical trials. Phytother Res. 2020 Oct;34(10):2628-2638.
  25. Sharif SN, Darsareh F. Impact of evening primrose oil consumption on psychological symptoms of postmenopausal women: a randomized double-blinded placebo-controlled clinical trial. Menopause. 2020 Feb;27(2):194-198.
  26. da Costa Hime LFC, Carvalho Lopes CM, Roa CL et al. Is there a beneficial effect of gamma-linolenic acid supplementation on body fat in postmenopausal hypertensive women? A prospective randomized double-blind placebo-controlled trial. Menopause. 2021 Feb 1;28(6):699-705.
  27. Pastor R, Bouzas C, Tur JA. Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis. Free Radic Biol Med. 2021 Aug 20;172:372-385.
  28. Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011 Feb 16;(2):CD002948.
  29. Wang Q, Liu R, Chang M et al. Dietary oleic acid supplementation and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2022;62(9):2508-2525.
  30. Sellem L, Flourakis M, Jackson KG et al. Impact of Replacement of Individual Dietary SFAs on Circulating Lipids and Other Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials in Humans. Adv Nutr. 2022 Aug 1;13(4):1200-1225.
  31. Won JC, Kwon HS, Moon SS et al. γ-Linolenic Acid versus α-Lipoic Acid for Treating Painful Diabetic Neuropathy in Adults: A 12-Week, Double-Placebo, Randomized, Noninferiority Trial. Diabetes Metab J. 2020 Aug;44(4):542-554.
  32. Nasri K, Akrami S, Rahimi M et al.The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. Endocr Res. 2018 Feb;43(1):1-10.
  33. Timoszuk, M.; Bielawska, K.; Skrzydlewska, E. Evening Primrose (Oenothera biennis) Biological Activity Dependent on Chemical Composition. Antioxidants 2018, 7, 108.
  34. Chung BY, Park SY, Jung MJ et al. Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study. Ann Dermatol. 2018 Aug;30(4):409-416.
  35. Bamford JT, Ray S, Musekiwa A, van Gool C, Humphreys R, Ernst E. Oral evening primrose oil and borage oil for eczema. Cochrane Database Syst Rev. 2013 Apr 30;2013(4):CD004416.
  36. Kazemi F, Masoumi SZ, Shayan A, Oshvandi K. The Effect of Evening Primrose Oil Capsule on Hot Flashes and Night Sweats in Postmenopausal Women: A Single-Blind Randomized Controlled Trial. J Menopausal Med. 2021 Apr;27(1):8-14.
  37. Sharif SN, Darsareh F. Impact of evening primrose oil consumption on psychological symptoms of postmenopausal women: a randomized double-blinded placebo-controlled clinical trial. Menopause. 2020 Feb;27(2):194-198.
  38. Mahboubi M. Evening Primrose (Oenothera biennis) Oil in Management of Female Ailments. J Menopausal Med. 2019 Aug;25(2):74-82.
  39. Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011 Feb 16;(2):CD002948. 
  40. Khorshidi M, Zarezadeh M, Moradi Moghaddam O et al. Effect of evening primrose oil supplementation on lipid profile: A systematic review and meta-analysis of randomized clinical trials. Phytother Res. 2020 Oct;34(10):2628-2638.
  41. Brosche T, Platt D. Effect of borage oil consumption on fatty acid metabolism, transepidermal water loss and skin parameters in elderly people. Arch Gerontol Geriatr. 2000 Mar-Apr;30(2):139-50.
  42. Hashemian SM, Mortaz E, Shafigh N et al. Effectiveness of Borage plus syrup on COVID-19 patients in intensive care units. Front Nutr. 2022 Nov 15;9:975937.
  43. Yue Y, Jin F, Yue X. The effect of Borago officinalis on the signaling pathway of the NLRP3 inflammasome complex, TLR4 and some inflammatory cytokines in type II diabetic patients with acute respiratory distress syndrome. Cell Mol Biol (Noisy-le-grand). 2021 Nov 25;67(3):178-183. 
  44. Tahvonen RL, Schwab US, Linderborg KM et al. Black currant seed oil and fish oil supplements differ in their effects on fatty acid profiles of plasma lipids, and concentrations of serum total and lipoprotein lipids, plasma glucose and insulin. J Nutr Biochem. 2005 Jun;16(6):353-9.
  45. Mińkowski K, Grześkiewicz S, Jerzewska M. Ocena wartości odżywczej olejów roślinnych o dużej zawartości kwasów linolenowych na podstawie składu kwasów tłuszczowych, tokoferoli i steroli. Żywn Nauk Technol Jakość 2011, 2: 124-135.
  46. Šavikin KP, Ðorđević BS, Ristić MS, et al. Variation in the fatty-acid content in seeds of various black, red, and white currant varieties. Chem Biodivers 2013, 10(1): 157-165.
  47. Leventhal LJ, Boyce EG, Zurier RB. Treatment of rheumatoid arthritis with blackcurrant seed oil. Rheumatology 1994, 33(9): 847-852.
  48. Wu D, Meydani M, Leka LS, et al. Effect of dietary supplementation with blackcurrant seed oil on the immune response of healthy elderly subjects. Am J Clin Nutr 1999, 70: 536-543.
  49. Deferne JL, Leeds AR. Resting blood pressure and cardiovascular reactivity to mental arithmetic in mild hypertensive males supplemented with blackcurrant seed oil. J Hum Hypertens 1996, 10: 531-537.
  50. Frost F, Kacprowski T, Rühlemann M et al. Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function. Gut. 2021 Mar;70(3):522-530.
  51. Leech B, McIntyre E, Steel A, Sibbritt D. Risk factors associated with intestinal permeability in an adult population: A systematic review. Int J Clin Pract. 2019 Oct;73(10):e13385. 
  52. Haro C, Rangel-Zúñiga OA, Alcalá-Díaz JF et al. Intestinal Microbiota Is Influenced by Gender and Body Mass Index. PLoS One. 2016 May 26;11(5):e0154090.
  53. Zhernakova A, Kurilshikov A, Bonder MJ et al.; LifeLines cohort study; Weersma RK, Feskens EJ, Netea MG et al. Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. Science. 2016 Apr 29;352(6285):565-9.
  54. Thaiss CA, Levy M, Grosheva I et al.Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection. Science. 2018 Mar 23;359(6382):1376-1383.
  55. D’Argenio V, Salvatore F. The role of the gut microbiome in the healthy adult status. Clin Chim Acta. 2015 Dec 7;451(Pt A):97-102.

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